PeproTech原装 300-21 重组人嗜酸性粒细胞趋化因子（CCL11）Catalog Number:
300-21
Synonyms:
CCL11
Description:
Eotaxin is a CC chemokine that signals through the CCR3 receptor. It is produced by IFN-γ-stimulated endothelial cells ａnd TNF-activated monocytes. Eotaxin selectively chemoattracts eosinophils and, along with Eotaxin-2 ａnd Eotaxin-3, plays a key role in the regulation of eosinophil recruitment in the asthmatic lung ａnd in allergic reactions. Recombinant Human Eotaxin is an 8.3 kDa protein containing 74 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.
AA Sequence:
GPASVPTTCC FNLANRKIPL QRLESYRRIT SGKCPQKAVI FKTKLAKDIC ADPKKKWVQD SMKYLDQKSP TPKP
Source:
E.coli
Purity:
Greater than 98% by SDS-PAGE gel ａnd HPLC analyses.
Biological Activity:
Determined by its ability to chemoattract human peripheral blood eosinophils using a concentration range of 0.1-10.0 ng/ml.
Cross Reactivity:
Mouse, Human + Hamster, Human + Guinea Pig, Human, Leech, Rat, Guinea Pig, Bacteria, N/A
Research Interests:
 | Chemotaxis |  | Immune System |
 | Wound Healing | |
Country of Origin:
USA
