DNA-PK / PRKDC，Rabbit Monoclonal Antibod_详细资料

产品信息

DNA-PK / PRKDC，Rabbit Monoclonal Antibod
【反应特异性】Human
【克隆 ID】EPR392
【用途】WB , ICC
【抗原分子量】460kDa

DNA-PK / PRKDC
Rabbit Monoclonal Antibody

Cas 号：

分子式：

别名：

PRKDC antibody, DNA-PKcs antibody, DNAPK antibody, DNPK1 antibody, HYRC antibody, HYRC1 antibody, XRCC7 antibody, p350 antibody, DNA-dependent protein kinase catalytic subunit antibody, DNPK1 antibody, p460 antibody

订货信息：

货号	品名	规格	包装	单价	货期	订购
	DNA-PK / PRKDC		100ul	询价	现货	订购

性状：

【反应特异性】Human
DNA-PK / PRKDC，Rabbit Monoclonal Antibod

【克隆 ID】EPR392
【用途】WB , ICC
【抗原分子量】460kDa

质量标准：

【产品介绍】DNA-activated serine/threonine protein
kinase （DNA-PK） is a nuclear protein kinase that is
involved in DNA nonhomologous end joining （NHEJ）
required for double- strand brake repair and
V（D）J recombination. DNA-PK is composed of a
large catalytic subunit of ~470 kDa （DNA-PKcs） and a
DNA binding heterodimer of approximately 70- and
80-kDa subunits called Ku. （1-2）. Autophosphorylation
of DNA-PK correlates with loss of protein kinase
activity and dissociation of the DNA-PKcs-Ku complex.
DNA-PK phosphorylates Hsp90, p53 and c-Jun （3-4）.

DNA-PK / PRKDC，Rabbit Monoclonal Antibod
Recommended Applications

WB, ICC
Applications and Recommended Dilution Factors

WB: 1:1,000 - 10,000
ICC: 1:500 - 1000
Species Reactivity *

Human

*Species cross-reactivity is based on WB analysis

DNA-PK / PRKDC，Rabbit Monoclonal Antibod

Products Data

Western blot analysis on （A） K562, （B） Molt-4,
（C） MCF-7, （D） SH-SY5Y, （E） 293T, and （F） PC-3 cell
lysates using anti-DNA-PK / PRKDC RabMAb （cat. #3922-1）.

Specificity

A synthetic peptide corresponding to residues in
human DNA-PK / PRKDC was used as an immunogen.

贮存：

DNA-PK / PRKDC，Rabbit Monoclonal Antibod

Storage Condition and Buffer

Store at -20 °C. Antibody buffer, 0.01% sodium azide,
50% Glycerol and 0.05% BSA. Stable for 12 months from date
of receipt

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