Peprotech Recombinant Human beta-NGF
- 型号：Peprotech 450-01
- 产地：中国大陆
- 供应商：杰辉生物（北京）科技发展有限公司
- 供应商报价：电议
- 标签：Peprotech Recombinant Human beta-NGF,生物试剂,通用试剂,供应Peprotech Recombinant Human beta-NGF,杰辉生物（北京）科技发展有限公司
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Peprotech Recombinant Human beta-NGF（450-01）
Catalog Number:450-01Synonyms:NGF-βDescription:β-NGF is a neurotrophic factor structurally related to BDNF, NT-3 ａnd NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. β-NGF is a potent neurotrophic factor that signals through its receptor β-NGFR, ａnd plays a crucial role in the development ａnd preservation of the sensory ａnd sympathetic nervous systems. β-NGF also acts as a growth ａnd differentiation factor for B lymphocytes ａnd enhances B-cell survival. The functional form of human β-NGF is a noncovalently disulfide-linked homodimer, of two 13.5 kDa polypeptide monomers （240 total amino acid residues）. The three disulfide bonds are required for biological activity.AA Sequence:SSSHPIFHRG EFSVCDSVSV WVGDKTTATD IKGKEVMVLG EVNINNSVFK QYFFETKCRD PNPVDSGCRG IDSKHWNSYC TTTHTFVKAL TMDGKQAAWR FIRIDTACVC VLSRKAVRRASource:E.coliPurity:Greater than 98% by SDS-PAGE gel ａnd HPLC analyses.Biological Activity:determined by its ability to stimulate chick E9 DRG neurite outgrowth. The ED50 is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 106 units/mg. Cross Reactivity:Chicken, Hamster, Mouse, Rat, Human, LeechResearch Interests:
Angiogenesis/ Cardiovascular 
Chemotaxis 
Diabetes / Weight Regulation 
Inflammation 
Neurobiology 
Stem Cells & Differentiation 
Wound Healing Country of Origin:USA
