SNCG Human/重组人Gamma-突触核蛋白
- 产地：美洲
- 供应商：厦门慧嘉生物科技有限公司
- 供应商报价：电议
- 标签：SNCG Human/重组人Gamma-突触核蛋白,生物试剂,生化试剂,供应SNCG Human/重组人Gamma-突触核蛋白,厦门慧嘉生物科技有限公司
产品库
| Synonyms | Gamma-synuclein, Persyn, Breast cancer-specific gene 1 protein, Synoretin, SR, SNCG, BCSG1, PERSYN, PRSN, g-Synuclein. |
| Introduction | g-synuclein（Originally known as a breast cancer specific gene product, BCSG1） is an acidic neuronal protein of 127 amino acids. Gamma-Synuclein is a member of the Synuclein protein family, which is believed to be involved in the pathogenesis of neurodegenerative diseases. High levels of Gamma-Synuclein have been found in advanced breast carcinomas suggesting a correlation between overexpression of SNCG ａnd breast tumor development. Synuclein-Gamma is found mostly in the peripheral nervous system （in primary sensory neurons, sympathetic neurons, ａnd motor neurons） ａnd retina. SNCG is also identified in the brain, ovarian tumors, ａnd in the olfactory epithelium. SNCG expression in breast tumors is a marker for tumor progression. A modification in the expression of gamma-synuclein has been detected in the retina of Alzheimer＇s patients. |
| Description | g-Synuclein Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 127 amino acids ａnd having a molecular mass of 13,300 Dalton. The protein coding region of g-synuclein was amplified by RT-PCR ａnd cloned into an E.coli expression vector. g-synuclein was overexpressed in E. coli ａnd purified to apparent homogeneity by taking advantage of the thermosolubility of the protein ａnd by using conventional column chromatography techniques. |
| Source | Escherichia Coli. |
| Physical Appearance | Sterile filtered colorless solution. |
| Formulation | The protein （1mg/ml） contains 20mM Tris-HCl buffer （pH 7.5）, 0.1M NaCl ａnd 1mM MgCl2. |
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. |
| Purity | Greater than 95.0% as determined by（a） Analysis by RP-HPLC. （b） Analysis by SDS-PAGE. |
| Amino Acid Sequence | mdvfkkgfsi akegvvgave ktkqgvteaa ektkegvmyv gaktkenvvqsvtsvaektk eqanavseav vssvntvatk tveeaeniav tsgvvrkedl rpsapqqegv askekeevae eaqsggd. |
| Usage | Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
