"Recombinant Human IL-17美国Peprotech"特价/价格

Recombinant Human IL-17 (IL-17A)
产品编号:
200-17
别名:
IL-17,CTLA-8
描述:
The originally described IL-17 protein, now known as IL-17A, is a homodimer of two 136 amino acid chains, secreted by activated T-cells that act on stromal cells to induce production of proinflammatory and hematopoietic bioactive molecules. Today, IL-17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17A exhibits cross-species bioactivity between human and murine cells. Recombinant human IL-17A is a 31.0 kDa disulfide-linked homodimer of two 136 amino acid polypeptide chains.
氨基酸序列:
MIVKAGITIP RNPGCPNSED KNFPRTVMVN LNIHNRNTNT NPKRSSDYYN RSTSPWNLHR NEDPERYPSV IWEAKCRHLG CINADGNVDY HMNSVPIQQE ILVLRREPPH CPNSFRLEKI LVSVGCTCVT PIVHHVA
来源:
E.coli
纯度:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
生物活性:
Assay #1: The as determined by the dose-dependent induction of IL-6 in primary human foreskin fibroblasts was found to be approximately 2 ng/ml.
Assay #2: Measured by its ability to induce IL-6 production by NHDF cells.
交叉反应:
Mouse
研究领域:

	AIDS/ HIV		血管生成/ 心血管
	免疫系统		炎症

原产国:
USA
仅用于研究。不适用于诊断或ZL。

Contact Distributor   规格 A 5µg B 25µg   100µg   250µg   500µg   1mg

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