AFP甲胎蛋白（兔多克隆抗体）Alpha-Fetoprotein

AFP甲胎蛋白（兔多克隆抗体）

Alpha-Fetoprotein

广州健仑生物科技有限公司

甲胎蛋白（AFP）是一种糖蛋白，属于白蛋白家族，主要由胎儿肝细胞及卵黄囊合成。甲胎蛋白在胎儿血液循环中具有较高的浓度，出生后则下降，至生后2～3月甲胎蛋白基本被白蛋白替代，血液中较难检出，故在成人血清中含量极低。甲胎蛋白具有很多重要的生理功能，包括运输功能、作为生长调节因子的双向调节功能、免疫YZ、T淋巴细胞诱导凋亡等。甲胎蛋白与肝癌及多种肿瘤的发SF展密切相关，在多种肿瘤中均可表现出较高浓度，可作为多种肿瘤的阳性检测指标。目前临床上主要作为原发性肝癌的血清标志物，用于原发性肝癌的诊断及LX监测。所以AFP常用于鉴定肿瘤与非肿瘤性肝脏疾病、卵黄癌和其它细胞肿瘤。

我司还提供其它进口或国产试剂盒：登革热、疟疾、流感、A链球菌、合胞病毒、腮病毒、乙脑、寨卡、黄热病、基孔肯雅热、克锥虫病、违禁品滥用、肺炎球菌、军团菌、化妆品检测、食品安全检测等试剂盒以及日本生研细菌分型诊断血清、德国SiFin诊断血清、丹麦SSI诊断血清等产品。

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【产品介绍】

细胞定位：细胞浆

适用组织：石蜡/冰冻

阳性对照：胎肝

抗原修复：热修复（柠檬酸）

抗体孵育时间：30-60min

AFP甲胎蛋白（兔多克隆抗体）Alpha-Fetoprotein

专家观点
阿米巴病随我国卫生条件的改善和人民生活水平的提高，发病率已经有了非常明显的下降，但在门诊经常看到有患者被诊断，并长期服药达数月、数年之久。更有只有几个月大的婴儿被诊断为阿米巴病并给于KJ素ZL。故在疾病的诊断时一定要注意病史，如婴儿（尤其是城市婴儿）基本没有可能接触到溶组织内阿米巴包囊，除非与之有密切者患有阿米巴病；另外，不是每种阿米巴都是可以致病的，而患儿却因此被给与长期的KJ素ZL，反造成肠道菌群紊乱而导致腹泻加重。
阿米巴肠病是由于溶组织阿米巴（痢疾阿米巴）寄生于结肠内，引起阿米巴痢疾或阿米巴结肠炎。痢疾阿米巴也是根足虫纲中Z重要的致病种类，在一定条件下，并可扩延至肝、肺、脑、泌尿生殖系和其他部位，形成溃疡和脓肿。
流行病学
本病流行于全世界，多流行于热带和亚热带地区。其感染率高低与各地环境卫生、经济状况和饮食习惯等密切相关。在我国的分布一般农村高于城市，近年来由于我国卫生状况和生活水平的提高，急性阿米巴痢疾和脓肿病例，除个别地区外，已较为少见。
1.传染源
慢性病人、恢复期病人及健康的带虫者为本病的传染源。
2.传播途径
溶组织内阿米巴的传播方式有以下几种：①包囊污染水源可造成该地区的暴发流行；②在以粪便作肥料，未洗净和未煮熟的蔬菜也是重要的传播因素；③包囊污染手指、食物或用具而传播；④蝇类及蟑螂都可接触粪便，体表携带和呕吐粪便，将包囊污染食物而成为重要传播媒介。
3.流行特点
溶组织内阿米巴病发布广泛，在温带地区，该病可时有流行，而在热带及亚热带地区，其流行情况则尤为严重。其发病情况因时而异，以秋季为多，夏季次之。发病率男多于女，成年多于儿童，这可能与吞食含包囊的食物或年龄免疫有关。
病因
阿米巴的致病是虫体和宿主相互作用，并受多种因素影响的复杂过程。溶组织内阿米巴的侵袭力主要表现在对宿主组织的溶解性破坏作用。
溶组织内阿米巴大滋养体，侵袭肠壁引起阿米巴病，常见的部位在盲肠，其次为直肠、乙状结肠和阑尾，横结肠和降结肠少见，有时可累及大肠全部或一部分回肠。

AFP甲胎蛋白（兔多克隆抗体）Alpha-Fetoprotein

我司还提供其它进口或国产试剂盒：登革热、疟疾、流感、A链球菌、合胞病毒、腮病毒、乙脑、寨卡、黄热病、基孔肯雅热、克锥虫病、违禁品滥用、肺炎球菌、军团菌、化妆品检测、食品安全检测等试剂盒以及日本生研细菌分型诊断血清、德国SiFin诊断血清、丹麦SSI诊断血清等产品。

想了解更多的产品及服务请扫描下方二维码：

【公司名称】 广州健仑生物科技有限公司
【市场部】    杨永汉

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【腾讯  】 
【公司地址】 广州清华科技园创新基地番禺石楼镇创启路63号二期2幢101-103室

expert's point
With the improvement of China's sanitary conditions and the improvement of people's living standard, the incidence of amebiasis has dropped significantly. However, patients are often diagnosed in outpatient clinics for several months and several years. More infants of only a few months old are diagnosed with amoebiasis and given antibiotic treatment. Therefore, in the diagnosis of the disease must pay attention to the medical history, such as infants (especially in urban infants) is unlikely to be exposed to E. histolytica amoeba cyst, unless closely followed by those with amoebiasis; In addition, not every Amoeba can be pathogenic, but children are therefore given long-term antibiotic treatment, anti-intestinal flora caused by the disorder leading to increased diarrhea.
Amoeba enteropathy is due to histolytic amoeba (dysentery amoeba) parasitic in the colon, causing amoebic dysentery or amoeba colitis. Diarrhea Amoeba is also the most important pathogenic species of the genus Footworm, under certain conditions, and can be extended to the liver, lung, brain, genitourinary tract and other parts of the formation of ulcers and abscesses.
Epidemiology
The disease is endemic in the world, more popular in tropical and subtropical regions. The prevalence of infection is closely related to the environmental health, economic conditions and eating habits in various places. In our country, the distribution of rural areas is generally higher than that of urban areas. In recent years, acute cases of amoebic dysentery and abscess have been rare in some regions, due to the improvement of China's health status and living standard.
Source of infection
Chronic patients, convalescent patients and healthy worms as the source of infection of the disease.
2. The route of transmission
Entamoeba histolytica transmission in the following ways: ① cysts contaminated water can cause outbreaks in the region; ② in the manure as fertilizer, unwashed and uncooked vegetables is also an important source of transmission; ③ Cystic contamination of fingers, food or appliances and spread; ④ flies and cockroaches can contact with excrement, body surface and vomit carrying manure will be contaminated by cystic food has become an important media.
3 popular features
Echinococcosis is widespread and in endemic areas the disease is endemic, while in the tropics and subtropics it is particularly prevalent. The incidence varies from time to time as much as in autumn, followed by summer. The incidence of male than female, adult more than children, which may be swallowed cysts containing food or age-related immunity.
Etiology
The pathogenesis of amoeba is a complex process in which the parasites interact with the host and are affected by many factors. Entamoeba histolytica invasion is mainly manifested in the dissolution of the host tissue destruction.
Entamoeba histolytica trophozoites, invasion of intestinal wall caused by amoebiasis, the common site in the cecum, followed by the rectum, sigmoid and appendix, transverse colon and descending colon rare, and sometimes can affect all or part of the large intestine ileum.