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Anti-Mouse CD25 Purified ebioscienc...

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Anti-Mouse CD25 Purified ebioscience


产品名称:Anti-Mouse CD25 Purified ebioscience
产品货号:14-0251-85
产品规格:500 ug
产品品Pai:eBioscience

 

Details

 

 

HostRat
IsotypeIgG1, lambda
ReactivityMouse
ConjugatePurified
Reported ApplicationsFlow Cytometric Analysis

 

 

Description

 

 

Description: The PC61.5 antibody reacts with mouse CD25, the 55 kDa interleukin-2 receptor alpha chain (IL-2R alpha). CD25 is expressed by early progenitors of the T and B lineage as well as by activated mature T and B lymphocytes. By itself, CD25 binds IL-2 only with low affinity. However, CD25 associates with CD122 (IL-2 receptor beta chain) and CD132 (common gamma chain) to form the high affinity IL-2 receptor. Binding of IL-2 to both the high and low affinity classes of IL-2 receptor is inhibited by the PC61.5 antibody. CD25 plays a role in lymphocyte differentiation and activation/proliferation.

 


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