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胸腺素 beta 4抗体

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胸腺素 beta 4抗体

英文名称 Thymosin beta 4
中文名称 胸腺素 beta 4抗体
别    名 FX; Hematopoietic system regulatory peptide; Prothymosin beta 4; PTMB 4; PTMB4; Seraspenide; T beta 4; T beta-4; TB4X; THYB 4; Thyb4; Thymosin beta 4; Thymosin beta-4; Thymosin beta 4 X chromosome; Thymosin beta 4 X linked; TMSB 4; TMSB4; TMSB4X; TYB4_HUMAN.
 
说 明 书 0.1ml  0.2ml  
研究领域 心血管  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 4.7kDa
细胞定位 细胞浆 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Thymosin beta 4
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
This gene encodes an actin sequestering protein which plays a role in regulation of actin polymerization. The protein is also involved in cell proliferation, migration, and differentiation. This gene escapes X inactivation and has a homolog on chromosome Y. [provided by RefSeq, Jul 2008]

Function:
Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Seraspenide inhibits the entry of hematopoeitic pluripotent stem cells into the S-phase.

Subunit:
Interacts with SERPINB1. Identified in a complex composed of ACTA1, COBL, GSN AND TMSB4X.

Subcellular Location:
Cytoplasm, cytoskeleton.

Tissue Specificity:
Expressed in several hemopoietic cell lines and lymphoid malignant cells. Decreased levels in myeloma cells.
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xy-0309R-AF555    Rabbit Anti-pig IgG/Alexa Fluor 55lexa Fluor 555标记的兔抗猪IgG
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xy-0309R-xyE-xyy5.5    Rabbit Anti-pig IgG/PE-Cy5.5PE-Cy5.5标记的兔抗猪IgG
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xy-0309R-FITxy    Rabbit Anti-pig IgG/FITCFITC标记的兔抗猪IgG
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