G2 and S phase expressed 1抗体

G2 and S phase expressed 1抗体

英文名称 G2 and S phase expressed 1
中文名称 G2期/S期应答相关蛋白1抗体
别    名 B99; B99 homolog; G 2 and S phase expressed 1; G two S phase expressed protein 1; GTSE 1; GTSE1_HUMAN .
G2 and S phase expressed 1抗体    
说 明 书 0.2ml  
研究领域 肿瘤  细胞生物  染色质和核信号  信号转导  细胞凋亡  细胞周期蛋白  转录调节因子  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Cow, Horse, Sheep, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 77kDa
细胞定位 细胞浆 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human GTSE1/G2 and S phase expressed 1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
The protein encoded by this gene is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis. 

Function:
May be involved in p53-induced cell cycle arrest in G2/M phase by interfering with microtubule rearrangements that are required to enter mitosis. Overexpression delays G2/M phase progression. 

Subcellular Location:xy-13833R    CENPBD1CENPBD1蛋白抗体
xy-13834R    CENPI着丝粒蛋白I抗体
xy-13835R    CENPJ着丝粒蛋白J抗体
xy-13836R    CENPL着丝粒蛋白L抗体
xy-13837R    CENPM着丝粒蛋白M抗体
xy-13838R    CENPN着丝粒蛋白N抗体
xy-13839R    CENPQ着丝粒蛋白Q抗体
xy-13842R    Centaurin beta 2CENTB2蛋白抗体
xy-13840R    CENPQ着丝粒蛋白Q抗体
xy-13841R    Centaurin alpha 2CENTA2蛋白抗体
xy-13843R    CENTB1胞吞再循环相关衔接蛋白CENTB1抗体
xy-13844R    phospho-CENTB1 (Ser554)磷酸化胞吞再循环相关衔接蛋白CENTB1抗体
xy-13845R    CENTD1CENTD1蛋白抗体
xy-13846R    CENTG3CENTG3蛋白抗体
xy-13847R    Centrin 3ZX体蛋白3抗体
xy-13848R    Centrin-1+Centrin-2ZX体蛋白1+2抗体
xy-13849R    Centrin 2ZX体蛋白2抗体
xy-13850R    CEP120ZX体蛋白CEP120抗体
xy-13851R    CEP164ZX体蛋白CEP128抗体
xy-13852R    CEP170ZX体蛋白CEP170抗体
xy-12301R    CDX4尾型同源盒转录因子4抗体
xy-11048R    CUTC铜转运蛋白CUTC抗体
xy-12931R    CUTL1CUTL1蛋白抗体
xy-12932R    CTNS胱氨酸抗体
xy-12933R    CTRB1胰凝乳蛋白酶B抗体
xy-12934R    CTRP2补体C1q肿瘤坏死因子相关蛋白2抗体
xy-12935R    CSTF3细胞分化促进因子77抗体
xy-12936R    CSTL1半胱氨酸蛋白酶YZ剂样蛋白1抗体
xy-12937R    CTBSCTBS蛋白抗体
xy-12938R    CSGALNACT1硫酸软骨素β1/β-1,4-GalNAc-T抗体
xy-12939R    CSGLCAT硫酸软骨素聚合酶3抗体
xy-12940R    Placental lactogen I+II胎盘催乳素1/2抗体
xy-12941R    CSK酪氨酸激酶C-SRC抗体
Cytoplasm, cytoskeleton. Note=Associated with microtubules. 

Post-translational modifications:
Phosphorylated in mitosis (By similarity).