产品信息
mTOR Inhibitor, WYE-132
Product Name: mTOR Inhibitor, WYE-132
Alternate Name/Synonyms: 1-{4-[1-(1,4-Dioxa-spiro[4.5]dec-8-yl)-4-(8-oxa-3-aza-bicyclo[3.2.1]oct-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl]-phenyl}-3-methyl-urea; WYE-125132
Description: Cell-permeable. A potent, selective, and ATP-competitive mTOR (mammalian Target Of Rapamycin) inhibitor (IC₅₀ = 0.19 nM). Displays >5000-fold selectivity over PI3Ks. WYE-132 inhibits mTORC1 and mTORC2 in diverse cancer models in vitro and in vivo.
Peptide Sequence: N/A
Appearance: White solid
Formulation: N/A
CAS Number: 1144068-46-1
Molecular Formula: C27H33N7O
Molecular Weight: 519.6
Purity: ≥98% by HPLC
Solubility: DMSO (50 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack Protect from light and moisture
Handling:
USAGE: For Research Use Only! Not For Use in Humans
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