Sigma D1515 Doxorubicin;Doxorubicin hydrochlori...

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Doxorubicin hydrochloride  阿霉素
货号：D1515
品外：阿霉素/Doxorubicin/Doxorubicin hydrochloride/盐酸阿霉素
产地：Sigma
价格：1850
产品名称：盐酸多柔比星/阿霉素
CAS No.： 25316-40-9
详细介绍：
中文名：盐酸多柔比星，盐酸阿霉素
化学名：8S-cis）-10-[（3-氨基-2,3,6-三去氧-a-L-来苏己吡喃基）-氧]-7,8,9,10-四氢-6,8,11-三羟基-8-羟基乙酰基-1-甲氧基-5,12-并四苯二酮盐酸盐
英文名：Doxorubicin HCL/Adriamycin HCL
分子量：579.99
分子式：C27H30ClNO11
Sigma相关资料如下：
Sigma  D1515  Doxorubicin hydrochloride   ≥98% （TLC）
Synonym: Adriamycin® hydrochloride, DOX, Hydroxydaunorubicin hydrochloride
CAS Number: 25316-40-9
Linear Formula: C27H29NO11 • HCl
Molecular Weight: 579.98
Beilstein Registry Number: 4229251
EC Number: 246-818-3
MDL number: MFCD00077757
PubChem Substance ID: 24893465
Description
Frequently Asked Questions Live Chat and Frequently Asked Questions  are available for this Product.
Biochem/physiol Actions Antitumour antibiotic. Effect of adriamycin on heart mitochondrial DNA;1 Properties.2,3
Inhibitor of reverse transcriptase and RNA polymerase; immunosuppressive agent; intercalates in DNA.
Naturally fluorescent anthracycline antibiotic, anticancer drug. Doxorubicin is a substrate of MRP1 which was first cloned from a DOX-resistant lung cancer cell line. Fluorescent property has been exploited for the measurement of drug efflux pump activities as well as resolving the important question of intracellular localization of various multidrug resistance proteins and the role of subcellular organelles （Golgi and lysosome） in the sequestration of drugs and its implication in drug resistant phenotypes.
Legal Information Adriamycin is a registered trademark of Farmitalia Carlo Erba S.R.L.
性质
assay ≥98% （TLC）
mp 216 °C （dec.）（lit.）
storage temp. 2-8°C