C型钠利尿多肽抗体

英文名称 Atrial natriuretic peptide
中文名称 C型钠利尿多肽抗体
别    名 NPPC; ANP; C type natriuretic peptide precursor; C-type natriuretic peptide; CNP-22; CNP-29; CNP-53; CNP; CNP2; Natriuretic peptide precursor C; pro-natriuretic peptide; ANFC_HUMAN; CNP-53; CNP2; Natriuretic peptide C.
C型钠利尿多肽抗体
说 明 书 0.1ml  0.2ml  
研究领域 心血管  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 14kDa
细胞定位 分泌型蛋白 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human proCNP (75-126aa)
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

产品介绍 background:
Natriuretic peptides comprise a family of 3 structurally related molecules: atrial natriuretic peptide (ANP; MIM 108780), brain natriuretic peptide (BNP; MIM 600295), and C-type natriuretic peptide, CNP, encoded by a gene symbolized NPPC. These peptides possess potent natriuretic, diuretic, and vasodilating activities and are implicated in body fluid homeostasis and blood pressure control.

Function:
Hormone which plays a role in endochondral ossification through regulation of cartilaginous growth plate chondrocytes proliferation and differentiation. May also be vasoactive and natriuretic. Specifically binds and stimulates the cGMP production of the NPR2 receptor. Binds the clearance receptor NPR3

Subcellular Location:
Secreted.

Similarity:
Belongs to the natriuretic peptide family.

Gene ID:
4880

Database links:

Entrez Gene: 4880 Human

Entrez Gene: 18159 Mouse

Entrez Gene: 114593 Rat

Omim: 600296 Human

SwissProt: P23582 Human

SwissProt: Q61839 Mouse

SwissProt: P55207 Rat

Unigene: 247916 Human

Unigene: 12802 Mouse

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