100ug 重组人TNF-alpha 100ug

Synonyms :

Tumor Necrosis Factor, TNFSF2, Cachectin, Differentiation-inducing factor （DIF）, Necrosin, Cytotoxin

Description :

TNF-α is a pleiotropic pro-inflammatory cytokine secreted by various cells including adipocytes, activated monocytes, macrophages, B cells, T cells and fibroblasts. It belongs to the TNF family of ligands and signals through two receptors, TNFR1 and TNFR2. TNF-α is cytotoxic to a wide variety of tumor cells and is an essential factor in mediating the immune response against bacterial infections. TNF-α also plays a role in the induction of septic shock, auto immune diseases, rheumatoid arthritis, inflammation, and diabetes. Recombinant human TNF-α is a soluble 157 amino acid protein （17.4 kDa） which corresponds to C-terminal extracellular domain of the full length transmembrane protein.

Catalog #:

300-01A

Source :

E.coli

Purity :

Greater than 98% by SDS-PAGE gel and HPLC analyses.