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标准品 黄绿青霉素/Citreoviridin

产品信息

黄绿青霉素/Citreoviridin

Source: Penicillium sp.
Synonyms Citreoviridin A
Description: Neurotoxic mycotoxin from Penicillium toxicarium, Penicillium ochrosalmoneum, Penicillium ochrosalmoneum, Aspergillus terreus, Penicillium citreo-viride and several other related fungi. Citreoviridin is believed to be the cause of the Acute Cardiac Beri-Beri disease.
CAS number: 25425-12-1
Merck index: 14: Not listed
Molecular weight: 412
Structure:


Citreoviridin

Molecular Formula: C23H30O6
Solubility
information:
Citreoviridin is soluble in benzene, ethanol, chloroform, ether,  dichloromethane.

Citreoviridin is hardly soluble in water (enough to give it yellow color) and hexane

Specifications  
Appearance: Orange-yellow powder
Purity: At least 97% by TLC, HPLC
λmax: 390, 294, 204nm
Melting point 110°C 
Solubility 10 mg of Citreoviridin gives clear yellow solution in 1 ml of DMSO, Methanol, Dichloromethane.
Storage -18°C, PROTECT FROM LIGHT
Applications As other Aurovertin group members, Citreoviridin binds to and inhibit mitochondrial ATPase, thereby uncoupling oxidative phosphorylation. Aurovertins are used as biochemical tools.
Warnings  
Classification Aurovertin class mycotoxin
Related products  
  For Research use only. Not for Human or Drug use
GMP/API grade available on request
Citreoviridin by Fermentek is not produced from or contains any ingredients from animal origin.
No genetically modified organisms are used.
Publications  
  Vieta I, Savarino A, Papa G, Vidotto V, Cantamessa C, Pugliese A.
In vitro inhibitory activity of citreoviridin against HIV-1 and an HIV-associated opportunist: Candida albicans.
J Chemother. 1996 Oct;8(5):351-7
  Sayood SF, Suh H, Wilcox CS, Schuster SM.
Effect of citreoviridin and isocitreoviridin on beef heart mitochondrial ATPase.
Arch Biochem Biophys. 1989 May 1;270(2):714-21.
  Wicklow DT, Stubblefield RD, Horn BW, Shotwell OL.
Citreoviridin levels in Eupenicillium ochrosalmoneum-infested maize kernels at harvest.
Appl Environ Microbiol. 1988 May;54(5):1096-8.
  Nishie K, Cole RJ, Dorner JW.
Toxicity of citreoviridin.
Res Commun Chem Pathol Pharmacol. 1988 Jan;59(1):31-52.
  Gause EM, Buck MA, Douglas MG.
Binding of citreoviridin to the beta subunit of the yeast F1-ATPase.
J Biol Chem. 1981 Jan 25;256(2):557-9.
  Satre M, Bof M, Vignais PV.
Interaction of Escherichia coli adenosine triphosphatase with aurovertin and citreoviridin: inhibition and fluorescence studies.
J Bacteriol. 1980 Jun;142(3):768-76.
  Linnett PE, Mitchell AD, Osselton MD, Mulheirn LJ, Beechey RB.
Citreoviridin, a specific inhibitor of the mitochondiral adenosine triphosphatase.
 
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