Zearalenone is a naturally occurring estrogen, a mycotoxin from resorcylic acid lactone group. It is named after the species name of the fungus that produces it.
CAS number:
17924-92-4
Merck index:
13,10169
Molecular weight:
318.4
Structure:
Molecular Formula:
C18H22O5
Solubility information:
Solubility of Zearalenone in water is about 0.002g/100ml. Zearalenone is slightly soluble in hexane and progressively more in benzene, acetonitrile, dichloromethane, methanol, acetone.
Specifications
Appearance:
White powder
Purity:
At least 98% by TLC, HPLC
λmax:
(in methanol) 236,274,316.
Melting point:
159°C - 163°C
Solubility:
Clear colourless solution at 5mg/ml Methanol
Storage:
-20°C.
Applications:
The resorcylic acid lactones have estrogenic activity. Zearalenone and its derivates were used as veterinary anabolic or estrogen substitutes.
Classification:
A resorcylic acid lactone Mycotoxin
Related products:
Deoxynivalenol (Vomitoxin), Brefeldin
Warnings:
For Research use only. Not for Human or Drug use GMP/API grade available on request 7AAD by Fermentek is not produced from or contains any ingredients from animal origin. No genetically modified organisms are used.
Publications
Songsermsakul P, Sontag G, Cichna-Markl M, Zentek J, Razzazi-Fazeli E. Determination of zearalenone and its metabolites in urine, plasma and faeces of horses by HPLC-APCI-MS. J Chromatogr B Analyt Technol Biomed Life Sci. 2006 Jul 7
Ding X, Lichti K, Staudinger JL. The mycoestrogen zearalenone induces CYP3A through activation of the pregnane X receptor. Toxicol Sci. 2006 Jun;91(2):448-55