DNA polymerase subunit II抗体

DNA polymerase subunit II抗体

英文名称 DNA polymerase subunit II
中文名称 DNA聚合酶α2抗体
别    名 DNA directed DNA polymerase alpha 2; DNA polymerase alpha 70 kDa subunit; DNA polymerase alpha subunit II; DNA polymerase subunit alpha B; DNA polymerase subunit II; FLJ21662; FLJ37250; Polymerase (DNA directed), alpha (70kD); DPOA2_HUMAN.
DNA polymerase subunit II抗体
说 明 书 0.2ml  
研究领域 细胞生物  细胞周期蛋白  细胞分化  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Cow, Horse, Sheep, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 66kDa
细胞定位 细胞核 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human POLA2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
May play an essential role at the early stage of chromosomal DNA replication by coupling the polymerase alpha/primase complex to the cellular replication machinery.

Function:
May play an essential role at the early stage ofchromosomal DNA replication by coupling the polymerasealpha/primase complex to the cellular replication machinery (Bysimilarity).

Subunit:
DNA polymerase alpha:primase is a four subunit enzymecomplex, which is assembled throughout the cell cycle, and consistsof the two DNA polymerase subunits A and B, and the DNA primaselarge and small subunits. Subunit B binds to subunit A. 

Subcellular Location:
Nucleus.

Post-translational modifications:
Phosphorylated in a cell cycle-dependent manner, in G2/M phase.xy-6718R    Dystrophin肌营养不良蛋白抗体
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xy-5835R    Drebrin脑发育调节蛋白抗体
xy-7648R    DFFBDNA断裂因子抗体（蛋白酶激活脱氧核糖核酸酶）
xy-7653R    DNase gamma脱氧核糖核酸酶γ抗体
xy-7659R    DATF1死亡相关转录因子1抗体
xy-7651R    DNase I脱氧核糖核酸酶1抗体
xy-7652R    DNase II脱氧核糖核酸酶2抗体
xy-6800R    DAD1细胞死亡防卫蛋白1抗体
xy-7592R    DARCDuffy血型趋化因子受体抗体
xy-0874R    DEKDEK癌基因结合蛋白
xy-12138R    DLGAP1PSD95结合蛋白1抗体
xy-12139R    DLGAP2PSD95结合蛋白2抗体
xy-12140R    DLGAP4PSD95结合蛋白4抗体
xy-7065R    DPF2双PHD-D4锌指蛋白2抗体
xy-7066R    DUSP22双特异性磷酸酶22抗体
xy-1276R    DNAJC10Erdj5/DNAJC10蛋白抗体
xy-7678R    DR6肿瘤细胞调亡素/肿瘤坏死因子受体死亡受体6抗体
xy-9427R    TMIGD1跨膜TMIGD1蛋白抗体
xy-11024R    DNAI1 + 2轴丝中链动力蛋白抗体
xy-11023R    DNAH7轴丝动力蛋白7抗体
xy-11778R    DORFIN环指蛋白19抗体
xy-11679R    delta 2 Cateninδ-连环蛋白抗体
xy-4307R    beta 2 Defensin防御素β2抗体
xy-11044R    phospho-DAB2 (Ser24)磷酸化信号转导功能磷蛋白DAB2抗体
xy-11431R    DUOX1双氧化酶1/甲状腺氧化酶1抗体
xy-11432R    DUOX2双氧化酶2/甲状腺氧化酶2抗体
xy-11433R    DUOXA1双氧化酶成熟因子抗体