1009298-09-2 AZD8055
- 型号：1009298-09-2
- 产地：USA
- 供应商：北京安必奇生物科技有限公司
- 供应商报价：面议
- 标签：AZD8055,13,北京安必奇生物科技有限公司
产品库
As a ATP-competitive inhibitor, AZD8055 can inihibit mTOR kinase with IC50 of 0.8 nM. AZD8055 shows inhibition to the phosphorylation of p70S6K and 4E-BP1, both of which are mTORC1 substrates. also can inhibit phosphorylation of the mTORC2 substrate AKT and downstream proteins. shows excellent selectivity (approximay 1,000-fold) against all class I phosphatidylinositol 3-kinase (PI3K) isoforms and other members of the PI3K-like kinase family.
As a ATP-competitive inhibitor, can inihibit mTOR kinase with IC50 of 0.8 nM. shows inhibition to the phosphorylation of p70S6K and 4E-BP1, both of which are mTORC1 substrates. also can inhibit phosphorylation of the mTORC2 substrate AKT and downstream proteins. shows excellent selectivity (approximay 1,000-fold) against all class I phosphatidylinositol 3-kinase (PI3K) isoforms and other members of the PI3K-like kinase family.
