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15(S)-Fluprostenol isopropyl ester

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    试剂描述:

    产品名称:15(S)-Fluprostenol isopropyl ester

    产品别名:15(S)-Flu-Ipr;

    CAS号:1420791-14-5

    英文别名:15(S)-Fluprostenol isopropyl ester

    分子量:500.6

    分子式:C26H35F3O6

    纯度:≥98%

    外观:见爱必信官网

    保存方法:Store at -20℃

    描述:15(S)-Fluprostenol isopropyl ester (15(S)-Flu-Ipr) is the unnatural C-15 epimer of Travoprost. Travoprost is the Alcon trade name for fluprostenol isopropyl ester, (Flu-Ipr) an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug.1,2 Flu-Ipr is a prodrug which is converted by esterase enzymatic activity in the cornea to yield the corresponding free acid. The free acid, fluprostenol, is a potent FP receptor agonist.3 In human and animal models of glaucoma, FP receptor agonist activity corresponds very closely with intraocular hypotensive activity. Although data is currently not available for the activity of 15(S)-Flu-Ipr, inversion of the stereochemistry at the 15 position of ocular hypotensive prostaglandins generally lowers the potency approximately 100 fold.4

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    产品信息订购:

      产品货号   产品名称   规格 价格 大包装及货期
      abs47045093   15(S)-Fluprostenol isopropyl ester   1mg  2095   立即咨询

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    温馨提示:不可用于临床ZL。
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