Phalloidin-iFluor 594 Conjugate

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试剂描述：

产品名称：Phalloidin-iFluor 594 Conjugate

产品别名：

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英文别名：

分子量：见爱必信官网

分子式：见爱必信官网

纯度：1000X stock solution in DMSO; 30 ul total

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保存方法：Store at -20° C

描述：

Phalloidin-iFluor 594 Conjugate Conjugate is a red fluorescent conjugate that is an excellent substitute for AlexFluor 594. Phalloidin is a heptapeptide phallotoxin produced by Amanita phalloides, the death cap mushroom. Phalloidin binds and stabilizes filamentous F-actin, preventing the dissociation of paired filaments and disturbing the natural equilibrium between filamentous (polymeric) and globular (monomeric) actin in the cell, as well as inhibit the ATP hydrolysis activity of F-actin. Actin is used by the cell for mechanical processes such as growth, scaffolding of the cytoskeleton, and locomotion, and disruption of this actin equilibrium destroys cellular functioning. The magnitude by which the actin protein differs from species to species is no more than 20%.
These properties of Phalloidin make Phalloidin iFluo  Conjugates a fantastic tool for labeling, identifying and quantitating F-actins. The Phalloidin iFluo  Conjugates are used at nanomolar concentrations with cell-free experiments, cell culture experiments, formaldehyde-fixed, permeabilized tissue sections and the study of actin networks. Because Phalloidin iFluor  Conjugates are offered in different colors the series is excellent for multicolor imaging applications.

应用：A fluorescent phalloidin conjugate that selectively binds to F-actins

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