LY2183240 2’-isomer

公告提醒：爱必信所有产品和服务仅用于科学研究，不用于临床应用及其他用途提供产品和服务（也不为任何个人提供产品和服务）!

试剂描述：

产品名称：LY2183240 2’-isomer

产品别名：5-[(1,1'-biphenyl)-4-ylmethyl]-N,N-dimethyl-2H-tetrazole-2-carboxamide

CAS号：1010096-65-7

英文别名：5-[(1,1'-biphenyl)-4-ylmethyl]-N,N-dimethyl-2H-tetrazole-2-carboxamide

分子量：307.4

分子式：C₁₇H₁₇N₅O

纯度：≥98%

外观：见爱必信官网

保存方法：Store at -20℃

描述：LY2183240 (Item No. 10008663) is a potent, competitive small molecule inhibitor of anandamide uptake (IC₅₀ = 270 pM; K_i = 540 pM) and hydrolysis.^1,2,3 It has been shown to increase anandamide levels in rat cerebellum (ED₅₀ = 1.37 mg/kg) and displays dose-dependent efficacy (3-30 mg/kg) in several rodent models of persistent pain.¹ LY2183240 2’-isomer is a less potent, 2,5-regioisomer of LY2183240 that inhibits anandamide hydrolysis and uptake with IC₅₀ values of 33 and 998 nM, respectively.²

应用：见爱必信官网

产品信息订购：

产品更多信息请进入爱必信网站咨询