CYM 5541

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试剂描述：

产品名称：CYM 5541

产品别名：CID-17253208;ML-249;

CAS号：945128-26-7

英文别名：N,N-Dicyclohexyl-5-cyclopropyl-1,2-oxazole-3-carboxamide

分子量：316.4

分子式：C₁₉H₂₈N₂O₂

纯度：≥98%

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保存方法：Store at -20℃

描述：The sphingosine 1-phosphate (S1P) receptor S1P₃ has roles in vasodilation, epithelial barrier function, cardioprotection, fibrosis, immunity, and inflammation.^1,2 CYM 5541 is a selective, allosteric agonist of S1P₃ (EC₅₀ = 72-132 nM).^3,4 It less effectively activates S1P₁ (EC₅₀ = 28-38 µM) and is ineffective at S1P₂, S1P₄, and S1P₅ as well as a panel of other receptors, ion channels and transporters.³

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