2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)

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产品名称：2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)

产品别名：dGMP;

CAS号：146877-98-7

英文别名：2'-DEOXYGUANOSINE 5'-MONOPHOSPHATE, DISO DIUM SALT HYDRATE

分子量：391.2

分子式：C₁₀H₁₂N₅O₇P • 2Na [XH₂O]

纯度：≥95%

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保存方法：Store at -20℃

描述：2'-Deoxyguanosine 5'-monophosphate (dGMP) is used as a substrate of guanylate kinases to generate dGDP, which in turn is phosphorylated to dGTP, a nucleotide precursor used in DNA synthesis. In addition, dGMP can be efficiently phosphorylated by the type I thymidylate kinase of the malarial agent P. falciparum.^1,2 In humans, deficiency of mitochondrial deoxyguanosine kinase, which synthesizes dGMP from ATP and deoxyguanosine, contributes to mitochondrial DNA depletion syndrome.^3,4

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