STAT5 Inhibitor

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试剂描述：

产品名称：STAT5 Inhibitor

产品别名：N′-((4-Oxo-4H-chromen-3-yl)methylene)nicotinohydrazide

CAS号：285986-31-4

英文别名：N′-((4-Oxo-4H-chromen-3-yl)methylene)nicotinohydrazide

分子量：293.28

分子式：C₁₆H₁₁N₃O₃

纯度：≥97%

外观：见爱必信官网

保存方法：Store at 4° C

描述：Stat5 Inhibitor is a cell permeable nonpetidic nicotinoyl hydrazone which suppresses Stat5 via binding to the SH2 domain. Studies indicate that Stat5 Inhibitor suppresses the SH2 domain of Stat1 and Stat3 to a lesser extent than Stat5 inhibition. In addition, Stat5/Stat5 DNA binding in K562 nuclear extracts are inhibited by Stat5 Inhibitor. Stat5 functions biologically in various processes such as homeostasis of hematopoietic stem cells, development of blood cells, growth hormone effects, and differentiation of mammary epithelium.

应用：A cell-permeable Stat5, SH2 domain target

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