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试剂描述： 产品名称：Tyrphostin 47 (RG-50864, AG-213) 产品别名：3,4-Dihydroxy-α-cyanothiocinnam-amide CAS号：122520-86-9 英文别名：3,4-Dihydroxy-α-cyanothiocinnam-amide 分子量：220.25 分子式：C10H8N2O2S 纯度：>97% 外观：见爱必信官网 保存方法：Store at -20° C 描述：Tyrphostin 47 is a protein tyrosine kinase inhibitor particularly potent against epidermal growth factor receptor (EGFR) kinase activity. Tyrphostin 47 has been observed to inhibit GTPase activity of transducin and the homologous insulin receptor kinase. It has also been found to also inhibit hyperactive motility of hamster spermatozoa. Tyrphostin 47 interferes with the proximal EGFR signaling pathway, causes G1-S transition arrest, and induces apoptosis in the human MCF-7 breast cancer cell line. In vero cell cultures, this product induced cell death and p38 MAPK phosphorylation. 应用：A potent inhibitor of EGFR kinase activity 产品信息订购：
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