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Diethylamine NONOate/AM,Diethylamine NONOate/AM,213768-16-2

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    试剂描述:

    产品名称:Diethylamine NONOate/AM

    产品别名:Diethylamine NONOate/AM

    CAS号:213768-16-2

    英文别名:Diethylamine NONOate/AM

    分子量:205.21

    分子式:C7H15N3O4

    纯度:≥95%

    外观:见爱必信官网

    保存方法:Store at -20° C

    描述:Diethylamine NONOate/AM is an esterase-sensitive and cell permeable, O2-acetoxymethylated diazeniumdiolate that acts as an intracellular NO donor. Diethylamine NONOate/AM is shown to induce apoptosis and to act as an antiproliferative agent in NO-sensitive human leukemia HL-60 and U937 cell lines (IC50 = 8.3 μM and 53 μM, respectively). The compound also suppresses oxidized low-density lipoprotein-induced caspase-3 activation in bovine aortic endothelial cells. Diethylamine NONOate/AM exhibits enhanced stability in physiological buffers. It may also be useful for examining temporally and spatially controlled NO availability.

    应用:An intracellular nitric oxide donor

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      产品货号   产品名称   规格 价格 大包装及货期
      abs42016914   Diethylamine NONOate/AM   1mg  2398   立即咨询

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