4'-[[(1-oxopentyl)phenylamino]methyl]-[1,1'-biphenyl]-2-carboxylic acid,2-[4-[(N-pentanoylanilino)methyl]phenyl]benzoic acid,862891-27-8

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试剂描述：

产品名称：4'-[[(1-oxopentyl)phenylamino]methyl]-[1,1'-biphenyl]-2-carboxylic acid

产品别名：2-[4-[(N-pentanoylanilino)methyl]phenyl]benzoic acid

CAS号：862891-27-8

英文别名：2-[4-[(N-pentanoylanilino)methyl]phenyl]benzoic acid

分子量：387.5

分子式：C₂₅H₂₅NO₃

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保存方法：Store at -20° C

描述：4'-[[(1-oxopentyl)phenylamino]methyl]-[1,1'-biphenyl]-2-carboxylic acid is a selective, potent full agonist for BLT2 (EC₅₀ = 20 nM). It does not displace [3H]-LTB4 binding to BLT1 at concentrations >1 µM and activates BLT2 at significantly lower concentrations than LTB₄ (EC₅₀ = 170 nM). 4'-[[(1-oxopentyl)phenylamino]methyl]-[1,1'-biphenyl]-2-carboxylic acid increases intracellular calcium stores in a dose-dependent manner, and induces ERK phosphorylation in Chinese hamster ovary (CHO) cells expressing BLT2 with no effect on CHO cells expressing BLT1.

应用：A BLT2 agonist

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