2'-Thioadenosine,(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-2-(hydroxymethyl)-4-sulfanyloxolan-3-ol,136904-69-3

公告提醒：爱必信所有产品和服务仅用于科学研究，不用于临床应用及其他用途提供产品和服务（也不为任何个人提供产品和服务）!

试剂描述：

产品名称：2'-Thioadenosine

产品别名：(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-2-(hydroxymethyl)-4-sulfanyloxolan-3-ol

CAS号：136904-69-3

英文别名：(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-2-(hydroxymethyl)-4-sulfanyloxolan-3-ol

分子量：283.3

分子式：C₁₀H₁₃N₅O₃S

纯度：见爱必信官网

外观：见爱必信官网

保存方法：Store at -20° C

描述：2'-Thioadenosine is a potent, selective, and irreversible inhibitor of the catalytic domain of the ErbB subfamily of protein tyrosine kinases. 2'-Thioadenosine inactivates epidermal growth factor receptor (ErbB1) via modification of a cysteine residue at the active site. This inactivation is reversed with the addition of 1mM dithiothreitol (DTT). 2'-Thioadenosine has also been shown to inhibit Neu/Her2 growth factor receptor (ErbB2, IC₅₀ = 45 µM).

应用：A potent, selective inhibitor of ErbB1/ErbB2

产品信息订购：

产品更多信息请进入爱必信网站咨询