(±)9,10-DiHOME-d4,(±)9,10-DiHOME-d4,263399-34-4(unlabeled)

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产品名称：(±)9,10-DiHOME-d4

产品别名：(±)9,10-DiHOME-d4

CAS号：263399-34-4(unlabeled)

英文别名：(±)9,10-DiHOME-d4

分子量：318.5

分子式：C₁₈H₃₀D₄O₄

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保存方法：Store at -20° C

描述：Contains four deuterium atoms at the 9, 10, 12, and 13 positions. Used as an internal standard for the quantification of (±)9,10-DiHOME by GC- or LC-mass spectrometry (MS). The unstable compound Leukotoxin is rapidly degraded by epoxide hydrolases to form the diol, 9,10-DiHOME. Mitochondrial dysfunction, vasodilation, and apoptosis are features of leukotoxin toxicity. In renal proximal tubular cells, the diol hydrolysis products of leukotoxin, such as 9,10-DiHOME, have been directly implicated as the cytotoxic agent responsible for cell death.

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