(±)-Lisofylline,利索茶碱,6493-06-7
- 品牌:absin
- 型号:abs42000472
- 产地:中国
- 供应商:爱必信(上海)生物科技有限公司
- 供应商报价:¥1200
- 标签:(±)-Lisofylline,利索茶碱,6493-06-7、(±)-Lisofylline,利索茶碱,6493-06-7价格、(±)-Lisofylline,利索茶碱,6493-06-7厂家、(±)-Lisofylline、Absin、爱必信(上海)生物科技有限公司
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试剂描述: 产品名称:(±)-Lisofylline 产品别名:LSF; BL 194; CT-1501R CAS号:6493-06-7 英文别名:LSF; BL 194; CT-1501R 分子量:280.3 分子式:C13H20N4O3 纯度:≥98% 外观:见爱必信官网 保存方法:Store at room temperature 描述:(±)-Lisofylline is a synthetic methylxanthine metabolite of Pentoxifylline and an inhibitor of phosphatidic acid generation. Suppression of lipopolysaccharide (LPS)-induced phosphatidic acid generation by (±)-Lisofylline was demonstrated to protect BALB/c mice against septic shock and LPS-associated endotoxin lethality. (±)-Lisofylline exhibits antiinflammatory effects, demonstrated to inhibit production of TNF-α stimulated by LPS, block the release of pro-inflammatory cytokines in response to oxidative injury, and inhibit interleukin-12 (IL-12) signaling activity. Suppression of IL-12 by (±)-Lisofylline is shown to interrupt activation of STAT4 (signal transducer and activator of transcription factor-4), blocking autoimmune deterioration of pancreatic β cells in non-obese diabetic mice. 应用:A synthetic methylxanthine with potent antiinflammatory action 产品信息订购:
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