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(±)-Lisofylline,利索茶碱,6493-06-7

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    试剂描述:

    产品名称:(±)-Lisofylline

    产品别名:LSF; BL 194; CT-1501R

    CAS号:6493-06-7

    英文别名:LSF; BL 194; CT-1501R

    分子量:280.3

    分子式:C13H20N4O3

    纯度:≥98%

    外观:见爱必信官网

    保存方法:Store at room temperature

    描述:(±)-Lisofylline is a synthetic methylxanthine metabolite of Pentoxifylline and an inhibitor of phosphatidic acid generation. Suppression of lipopolysaccharide (LPS)-induced phosphatidic acid generation by (±)-Lisofylline was demonstrated to protect BALB/c mice against septic shock and LPS-associated endotoxin lethality. (±)-Lisofylline exhibits antiinflammatory effects, demonstrated to inhibit production of TNF-α stimulated by LPS, block the release of pro-inflammatory cytokines in response to oxidative injury, and inhibit interleukin-12 (IL-12) signaling activity. Suppression of IL-12 by (±)-Lisofylline is shown to interrupt activation of STAT4 (signal transducer and activator of transcription factor-4), blocking autoimmune deterioration of pancreatic β cells in non-obese diabetic mice.

    应用:A synthetic methylxanthine with potent antiinflammatory action

    产品信息订购:

      产品货号   产品名称   规格 价格 大包装及货期
      abs42000472   (±)-Lisofylline   10mg  1200   立即咨询

    产品更多信息请进入爱必信网站咨询

    温馨提示:不可用于临床ZL。
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