rac O-Desmethyl Venlafaxine β-D-Glucuronide,rac O-Desmethyl Venlafaxine β-D-Glucuronide,1021933-98-1

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产品名称：rac O-Desmethyl Venlafaxine β-D-Glucuronide

产品别名：4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol Glucuronide; 4-[2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenyl β-D-Glucopyranosiduronic Acid

CAS号：1021933-98-1

英文别名：4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol Glucuronide; 4-[2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenyl β-D-Glucopyranosiduronic Acid

分子量：439.5

分子式：C₂₂H₃₃NO₈

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保存方法：Store at 4° C

描述：rac O-Desmethyl Venlafaxine ∫-D-Glucuronide is a metabolite of Venlafaxine . Venlafaxine is a derivative of phenylethylamine which is reported to facilitate neurotransmission within the central nervous system via blocking the presynaptic reuptake of neuroamines such as serotonin (5-hydroxytryptamine; 5-HT) and noradrenaline (norepinephrine). Velanfaxine is also reported to be a weak inhibitor of dopamine reuptake. In vitro studies indicate that Venlafaxine does not demonstrate significant activity for muscarinic, histaminergic or α-1 adrenergic receptors. The metabolism of venlafaxine is reported to occur by cytochrome P450 (CYP) enzyme CYP2D6 yielding O-desmethylvenlafaxine. A lesser metabolite, N-desmethylvenlafaxine is produced by CYP3A4.

应用：A metabolite of Venlafaxine

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