Rho Kinase Inhibitor V,N-[4-(1H-pyrazol-4-yl)phenyl]-2,3-dihydro-1,4-benzodioxine-3-carboxamide,1072906-02-5

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产品名称：Rho Kinase Inhibitor V

产品别名：N-[4-(1H-pyrazol-4-yl)phenyl]-2,3-dihydro-1,4-benzodioxine-3-carboxamide

CAS号：1072906-02-5

英文别名：N-[4-(1H-pyrazol-4-yl)phenyl]-2,3-dihydro-1,4-benzodioxine-3-carboxamide

分子量：321.3

分子式：C₁₈H₁₅N₃O₃

纯度：见爱必信官网

外观：见爱必信官网

保存方法：Store at 4° C

描述：Rho Kinase Inhibitor V is a cell-permeable pyrazolyl carboxamide compound that acts as a potent, ATP-binding pocket-targeting inhibitor of Rock-2 (ROCK-II) and effectively inhibits the myosin light chain 2 phosphorylation on Thr18/Ser19 in A7r5 cells. Rho Kinase Inhibitor V affects the activities of PKA, MRCK, Akt1 and CYP-450 enzymes only at much higher concentrations.

应用：A cell-permeable and potent, ATP-binding pocket-targeting inhibitor of ROCK-II

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