Hispidulin,高车前素,1447-88-7

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试剂描述：

产品名称：Hispidulin

产品别名：Dinatin; Scutellarein 6-methyl ether

CAS号：1447-88-7

英文别名：Dinatin; Scutellarein 6-methyl ether

分子量：300.27

分子式：C₁₆H₁₂O₆

纯度：见爱必信官网

外观：Beige solid

保存方法：Desiccate at -20° C

描述：

Hispidulin is a natural flavanoid which acts as a potent benzodiazepine (BZD) receptor ligand. In addition, hispidulin competitively binds to the benzodiazepine receptor, thus inhibiting 3H-Flumazenil from binding to the receptor. Furthermore, it has been observed that hispidulin has antioxidant, antithrombotic, antifungal, and antiproliferative properties. Alternate studies indicate that hispidulin can inhibit the PI3K/Akt/mTOR signaling pathway in endothelial cells by targeting VEGF receptor 2. Inhibition of this receptor by hispidulin suppressed cell migration, invasion, and capillary-like structure formation of HU-VE-Cs in vascular endothelial cells. Hispidulin also aactivates AMPK.

应用：A potent benzodiazepine (BZD) receptor ligand

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