Adenosine Kinase Inhibitor,ABT 702 dihydrochloride,5-(3-Bromophenyl)-7-[6-(4-morpholinyl)-3-pyrido[2,3-d]byrimidin-4-aminedihydrochloride,214697-26-4

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产品名称：Adenosine Kinase Inhibitor

产品别名：ABT-702; 4-Amino-5-(3-bromophenyl)-7-(6-morpholino-pyridin-3-yl)pyrido[2,3-d]pyrimidine

CAS号：214697-26-4

英文别名：ABT-702; 4-Amino-5-(3-bromophenyl)-7-(6-morpholino-pyridin-3-yl)pyrido[2,3-d]pyrimidine

分子量：536.3

分子式：C₂₂H₁₉BrN₆O•2HCl

纯度：≥90%

外观：见爱必信官网

保存方法：Store at -20° C

描述：Adenosine Kinase Inhibitor is a cell-permeable, non-nucleoside pyridopyrimidine compound that acts as a potent, adenosine-competitive, and reversible ADK (adenosine kinase (AK)) inhibitor (IC₅₀ = 50.7 nM using intact IMR-32 cells and 1.7 nM in cell-free assays using rat brain cytosolic AK). The inhibitory effect is not species-specific and its pharmacological selectivity is confirmed using a panel of more than 80 other enzymes, ion channels, and receptors, including various adesine receptors.

应用：A cell-permeable compound that acts as a potent adenosine kinase inhibitor

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