5-trans U-46619,(E)-7-[(2S,3R)-3-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxabicyclo[2.2.1] heptan-2-yl]hept-5-enoic acid,330796-58-2

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试剂描述：

产品名称：5-trans U-46619

产品别名：7-[(2S,3R)-3-[(3S)-3-hydroxyoct-1-enyl]-5oxabicyclo[2.2.1]heptan-2-yl]hept-5enoic acid

CAS号：330796-58-2

英文别名：7-[(2S,3R)-3-[(3S)-3-hydroxyoct-1-enyl]-5oxabicyclo[2.2.1]heptan-2-yl]hept-5enoic acid

分子量：350.5

分子式：C₂₁H₃₄O₄

纯度：见爱必信官网

外观：A solution in methyl acetate

保存方法：Store at -20° C

描述：U-46619 is a TP receptor agonist that exhibits properties similar to Thromboxane A2, inducing platelet aggregation and vascular smooth muscle contraction. This is a minor impurity (2-5%) that is variably present in most commercial preparations of U-46619. The biological activity of 5-trans U-46619 has rarely been tested separately from U-46619 itself. The only case published to date, 5-trans U-46619 was found to be half as potent of an inhibitor of Prostaglandin E synthase as the 5-cis version of U-46619.

应用：A Prostaglandin H2/thromboxane A2 receptor agonist

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