20-carboxy Arachidonic Acid,(5Z,8Z,11Z,14Z)-icosatetraenedioic acid,79551-84-1

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试剂描述：

产品名称：20-carboxy Arachidonic Acid

产品别名：(5Z,8Z,11Z,14Z)-icosatetraenedioic acid

CAS号：79551-84-1

英文别名：(5Z,8Z,11Z,14Z)-icosatetraenedioic acid

分子量：334.45

分子式：C₂₀H₃₀O₄

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外观：见爱必信官网

保存方法：Store at -20° C

描述：20-carboxy arachidonic acid (20-COOH-AA) inhibits ion transport in the kidneys, much like its parent compound 20-HETE. Studies have shown that 20-carboxy arachidonic acid produces vasorelaxation of porcine coronary microvessels constricted with endothelin. Additionally, 20-carboxy arachidonic acid binds to and activates the isolated ligand binding domains of peroxisome proliferator-activated receptor α (PPARα, K_d = 0.87 ± 0.12 µM) and PPARγ (K_d = 1.7 ± 0.5 µM).

应用：A PPARα and PPARγ activator

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