SU 16f,3-[2,4-dimethyl-5-[(2-oxo-6-phenyl-1H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid,251356-45-3

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试剂描述：

产品名称：SU 16f

产品别名：3-[2,4-dimethyl-5-[(2-oxo-6-phenyl-1H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid

CAS号：251356-45-3

英文别名：3-[2,4-dimethyl-5-[(2-oxo-6-phenyl-1H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid

分子量：386.44

分子式：C₂₄H₂₂N₂O₃

纯度：>98%

外观：见爱必信官网

保存方法：Store at room temperature

描述：SU 16f is a selective PDGFRβ inhibitor with an IC₅₀=10nM. In vitro studies demonstrate that SU 16f also inhibits HUVEC and NIH3T3 cell proliferation with an IC₅₀=0.11μM. In addition, SU 16f displays 14 fold selectivity towards PDGFRβ compared to Flk-1 (VEGFR2), 229-fold over Flg (FGFR1) and 10000-fold over EGFR. SU 16f is an inhibitor of Flk-1.

应用：A potent PDGFRβ inhibitor

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