Phosphodiesterase 4 Inhibitor,3,5-DIMETHYL-1-(3-NITROPHENYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER,346440-86-6

公告提醒：爱必信所有产品和服务仅用于科学研究，不用于临床应用及其他用途提供产品和服务（也不为任何个人提供产品和服务）!

试剂描述：

产品名称：Phosphodiesterase 4 Inhibitor

产品别名：3,5-DIMETHYL-1-(3-NITROPHENYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER

CAS号：346440-86-6

英文别名：3,5-DIMETHYL-1-(3-NITROPHENYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER

分子量：289.3

分子式：C₁₄H₁₅N₃O₄

纯度：≥97%

外观：见爱必信官网

保存方法：Store at 4° C

描述：Phosphodiesterase 4 Inhibitor is a pyrazole compound with a high-affinity active site binding inhibitor of PDE4B (phosphodiesterase IVB) and PDE4D (phosphodiesterase IVD) (IC₅₀ = 33 nM and 21 nM). More potent than Rolipram (IC₅₀ = 570 nM and 1.1 μM for PDEIVB and PDEIVD), respectively and greater selectivity over PDEIB, PDEIIA, PDEIIIB, PDEVA, PDEVIIB, PDEVIIIA, PDEIXA and PDEXIA (IC₅₀ > 30 μM) and minimally inhibit PDEXA with an IC₅₀ of 6.9 μM.

应用：A pyrazole compound with an active site binding inhibitor of phosphodiester

产品信息订购：

产品更多信息请进入爱必信网站咨询