PGI2·Na (Prostaglandin I2·Na, Prostacyclin),依前列醇钠,61849-14-7

公告提醒：爱必信所有产品和服务仅用于科学研究，不用于临床应用及其他用途提供产品和服务（也不为任何个人提供产品和服务）!

试剂描述：

产品名称：PGI2·Na (Prostaglandin I2·Na, Prostacyclin)

产品别名：Prostacyclin; Prostaglandin I₂; Epoprostenol; Epoprostenol Sodium Salt

CAS号：61849-14-7

英文别名：Prostacyclin; Prostaglandin I₂; Epoprostenol; Epoprostenol Sodium Salt

分子量：374.45

分子式：C₂₀H₃₁O₅•Na

纯度：≥98%

外观：见爱必信官网

保存方法：Store at -20° C

描述：PGI2·Na (Prostaglandin I2·Na, Prostacyclin) is primarily synthesized in macrovascular endothelial cells. It has been shown to induce vasodilation, inhibit platelet aggregation, as well as demonstrate fibrinolytic and cytoprotective activity. PGI2 binding to the G-protein coupled IP₁ receptor (PGI2 receptor), is believed to be responsible for the inhibition of platelet aggregation and vasodilation activity. PGI2 greatly increases cAMP concentrations, it is 30 times more active than PGE1, and 10 times more active than PGD2; however, it is a relatively unstable eicosanoid, with a half-life of about 2 minutes under physiological conditions. Analogues such as Iloprost have been developed with superior stability and similar potency for IP receptors. PGI2·Na (Prostaglandin I2·Na, Prostacyclin) is an activator of IP Receptor and an inhibitor of TXA2R.

应用：An eiconasoid shown to induce vasodilation and inhibit platelet aggregation

产品信息订购：

产品更多信息请进入爱必信网站咨询