NNC 711,1-[2-(benzhydrylideneamino)oxyethyl]-3,6-dihydro-2H-pyridine-5-carboxylic acid,hydrochloride,145645-62-1

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试剂描述：

产品名称：NNC 711

产品别名：NO-711 hydrochloride; 1,2,5,6-Tetrahydro-1-[2-[[(diphenylmethylene)amino]oxy] ethyl]-3-pyridinecarboxylic acid hydrochloride

CAS号：145645-62-1

英文别名：NO-711 hydrochloride; 1,2,5,6-Tetrahydro-1-[2-[[(diphenylmethylene)amino]oxy] ethyl]-3-pyridinecarboxylic acid hydrochloride

分子量：386.88

分子式：C₂₁H₂₂N₂O₃•HCl

纯度：≥99%

外观：见爱必信官网

保存方法：Desiccate at 4° C

描述：NNC 711 is a potent and selective inhibitor of GABA uptake by GABA T-1( (IC₅₀ values are 0.04, 171, 1700 and 622 μM for hGABA T-1, rGABA T-2, hGABA T-3 and hBGT-1 respectively). GABA transporters belong to the solute carrier family 6 (SLC6) and are sodium- and chloride-dependent members that mediate the rapid removal of GABA. NNC 711 also exhibits cognition-enhancing activity.

应用：A potent and selective inhibitor of GABA T-1

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