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Recombinant Human Lymphatic Endothelial Hyluronan Receptor-1

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    试剂描述:

    产品名称:Recombinant Human Lymphatic Endothelial Hyluronan Receptor-1

    产品别名:重组人淋巴内皮透明质酸受体-1;LYVE-1

    CAS号:见爱必信官网

    英文别名:LYVE-1

    分子量:见爱必信官网

    分子式:见爱必信官网

    纯度:0.9

    外观:Sterile Filtered colorless solution(LYVE-1 Human Recombinant protein at 100µg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol).

    保存方法:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles

    描述:

        LYVE-1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE-1 predicts a 322-residue type I integral membrane polypeptide 41% similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE-1 molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE-1 molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE-1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves.
     
        Soluble LYVE1 Human Recombinant fused to a GST-tag produced in E.Coli is a single, non-glycosylated, polypeptide containing 243-323 amino acids and having a total molecular mass of 36 kDa. 
        The LYVE-1 is purified by proprietary chromatographic techniques.

    应用:见爱必信官网

    产品信息订购:

      产品货号   产品名称   规格 价格 大包装及货期
      abs44074396   Recombinant Human Lymphatic Endothelial Hyluronan Receptor-1   2ug  3700   立即咨询

    产品更多信息请进入爱必信网站咨询

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