D,L-N,N-Didesmethyl-O-desmethyl Venlafaxine Hydrochloride,4-[2-amino-1-(1-hydroxycyclohexyl)ethyl]phenol,hydrochloride,135308-76-8

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产品名称：D,L-N,N-Didesmethyl-O-desmethyl Venlafaxine Hydrochloride

产品别名：4-[2-amino-1-(1-hydroxycyclohexyl)ethyl]phenol,hydrochloride

CAS号：135308-76-8

英文别名：4-[2-amino-1-(1-hydroxycyclohexyl)ethyl]phenol,hydrochloride

分子量：271.78

分子式：C₁₄H₂₁NO₂•HCl

纯度：见爱必信官网

外观：Off-White to Tan Solid

保存方法：Store at -20° C

描述：D,L-N,N-Didesmethyl-O-desmethyl Venlafaxine Hydrochloride is a metabolite of Venlafaxine . Venlafaxine is a derivative of phenylethylamine which is reported to facilitate neurotransmission within the central nervous system via blocking the presynaptic reuptake of neuroamines such as serotonin (5-hydroxytryptamine; 5-HT) and noradrenaline (norepinephrine). Velanfaxine is also reported to be a weak inhibitor of dopamine reuptake. In vitro studies indicate that Venlafaxine does not demonstrate significant activity for muscarinic, histaminergic or α-1 adrenergic receptors. The metabolism of venlafaxine is reported to occur by cytochrome P450 (CYP) enzyme CYP2D6 yielding O-desmethylvenlafaxine. A lesser metabolite, N-desmethylvenlafaxine is produced by CYP3A4.

应用：A metabolite of the reuptake inhibitor Venlafaxine

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