Apstatin,1-[1-(3-amino-2-hydroxy-4-phenylbutanoyl)pyrrolidine-2-carbonyl]-N-(1-amino-1-oxopropan-2-yl)pyrrolidine-2-carboxamide,160470-73-5

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试剂描述：

产品名称：Apstatin

产品别名：Aminopeptidase P Inhibitor

CAS号：160470-73-5

英文别名：Aminopeptidase P Inhibitor

分子量：459.54

分子式：C₂₃H₃₃N₅O₅

纯度：≥95%

外观：见爱必信官网

保存方法：Store at -20° C

描述：Apstatin is a selective inhibitor of aminopeptidase P (APP), with a K_i of 2.6 μM in rat lung membrane-bound APP. Apstatin is shown to increase Bradykinin-promoted cardioprotection in rats with artificially introduced myocardial infarctions by inhibiting the Bradykinin degradation action of APP. When combined with the angiotensin-converting enzyme inhibitors enalapril , lisinopril , or ramipril , decrease of myocardial infarction size was enhanced.

应用：A selective inhibitor of Aminopeptidase P (APP)

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