磷酸化红细胞阴离子交换蛋白1抗体,Anti-phospho-Band3(Tyr21)抗体

产品名称：磷酸化红细胞阴离子交换蛋白1抗体,(Tyr21)抗体 
中文名称：磷酸化红细胞阴离子交换蛋白1抗体 
英文名称：Anti-phospho-Band3 (Tyr21) 
产品编号：byk-12569R 
产品规格：0.1ml/0.2ml
产品用途：科研实验
亚 型： IgG
贮 存： 贮存于-20℃
抗体的异质性。抗体的组成极为复杂，是由成千上万、多种多样的免疫球蛋白（Ig）分子所组成。这些Ig分子在形状、大小、结构以及氨基酸的组成和排列上，既相似，又有差别。由于有差别，它们的电泳活性就有很大的变化。
磷酸化红细胞阴离子交换蛋白1抗体,(Tyr21)抗体 品说明：
Band 3, also designated AE1, is an erythrocyte membrane glycoprotein that contributes to cell stuctural integrity and mediates exchange of chloride and bicarbonate across the phospholipid bilayer. The diverse functions of the approximately 900 amino acid protein are mediated by two distinct domains. The amino terminal domain, also known as cdb3 for cytoplasmic domain of erthrocyte membrane band 3, acts as an attachment site for the erythrocyte skeleton by binding ankyrin. The carboxy-terminal, membrane-associated domain carries out exchange transport of anions. Degradation of band 3 can generate an aging antigen known as senescent cell antigen, or SCA, which is expressed on old cells and marks them for removal by the immune system. An isoform of band 3, which lacks the first 65 amino acids and does not bind ankryin, is expressed in kidney.
保存条件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 
磷酸化红细胞阴离子交换蛋白1抗体,(Tyr21)抗体 关产品：
Anti-Mcl-1(myeloid cell leukemia 1)  髓样细胞白血病-1抗体
Anti-MDM2 (urine double minute 2)  双微体2癌基因抗体
Anti-MDR1(multidrug resistance 1)  多药耐药蛋白抗体
Anti-MEF2(myocyte enhancer-binding factor 2)  肌细胞增强因子2抗体
Anti-Megsin/SER—PINB7  丝氨酸(或半胱氨酸)蛋白酶YZ剂B7抗体
Anti-Melamine  三聚氰胺抗体
Anti-Melamine  三聚氰胺抗体
Anti-Melan-A/MART-1  黑色素瘤相关抗原/黑色素-A抗体
Anti-M-enk  抗甲硫氨酸脑啡肽抗体
Anti-MEK1/MAPKK1/MEKK1(mitogen activated protein kinase kinase 1)  MEK1/MAPKK1抗体(N-端)
抗体结构:
抗体是具有4条多肽链的对称结构，其中2条较长、相对分子量较大的相同的重链(H链)；2条较短、相对分子量较小的相同的轻链(L链)。链间由二硫键和非共价键联结形成一个由4条多肽链构成的单体分子。轻链有κ和λ两种，重链有μ、δ、γ、ε和α五种。 整个抗体分子可分为恒定区和可变区两部分。在给定的物种中，不同抗体分子的恒定区都具有相同的或几乎相同的氨基酸序列。可变区位于"Y"的两臂末端。在可变区内有一小部分氨基酸残基变化特别强烈，这些氨基酸的残基组成和排列顺序更易发生变异区域称高变区。高变区位于分子表面，多由17个氨基酸残基构成，少则只有2 ～ 3个。高变区氨基酸序列决定了该抗体结合抗原抗原的特异性。一个抗体分子上的两个抗原结合部位是相同的，位于两臂末端称抗原结合片段(antigen-binding fragment, Fab)。"Y"的柄部称结晶片段(crystalline fragment,FC)，糖结合在FC 上。