公告提醒:爱必信所有产品和服务仅用于科学研究,不用于临床应用及其他用途提供产品和服务(也不为任何个人提供产品和服务)! YZ剂描述: 产品名称:PAR-4 Agonist Peptide, amide TFA 产品别名:见爱必信官网 英文别名:PAR-4 Agonist Peptide, amide TFA 靶点:PAR-4 CAS:1228078-65-6 纯度:98% 外观:见爱必信官网 保存方法:store at -20℃ for one year(Powder) 描述:PAR-4 Agonist Peptide, amide TFA (PAR-4-AP TFA; AY-NH2 TFA) is a proteinase-activated receptor-4 (PAR-4) agonist, which has no effect on either PAR-1 or PAR-2 and whose effects are blocked by a PAR-4 antagonist. 溶解性: In Vitro: DMSO : ≥ 250 mg/mL (314.54 mM) * "≥" means soluble, but saturation unknown. Preparing Stock Solutions ConcentrationSolventMass | 1 mg | 5 mg | 10 mg |
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1 mM | 1.2581 mL | 6.2907 mL | 12.5815 mL | 5 mM | 0.2516 mL | 1.2581 mL | 2.5163 mL | 10 mM | 0.1258 mL | 0.6291 mL | 1.2581 mL |
*请根据产品在不同溶剂中的溶解度,选择合适的溶剂配制储备液,并请注意储备液的保存方式和期限。 In Vivo: 请根据您的实验动物和给YF式选择适当的溶解方案,配制前请先配制澄清的储备液,再依次添加助溶剂(为保证实验结果的可靠性,体内实验的工作 液,建议您现用现配,当天使用;澄清的储备液可以根据储存条件,适当保存;以下溶剂前的百分比是指该溶剂在您配制终溶液中的体积占比): 1. 请依序添加每种溶剂: 10% DMSO 40% PEG300 5% Tween-80 45% saline Solubility: ≥ 2.08 mg/mL (2.62 mM); Clear solution 2. 请依序添加每种溶剂: 10% DMSO 90% (20% SBE-β-CD in saline) Solubility: ≥ 2.08 mg/mL (2.62 mM); Clear solution 3. 请依序添加每种溶剂: 10% DMSO 90% corn oil Solubility: ≥ 2.08 mg/mL (2.62 mM); Clear solution
* 体外研究: 体内研究: Compared with their BALB/cBy controls, SCID mice have a significantly greater abdominal response to colorectal distension (CRD) at the distension levels of 0.04 to 0.1 mL increasing the intensity of EMG response by 384% to 132%, respectively (P<0.01; P<0.01; P<0.01; P<0.001). PAR-4 activation effectively reverses this hypersensitivity (P<0.01, P<0.05; P<0.05; P<0.05). 产品信息订购: 产品货号 | 产品名称 | 规格 | 价格 | 大包装及货期 | abs820392 | PAR-4 Agonist Peptide, amide TFA | 1mg | 1320 | 立即咨询 | 产品更多信息请进入爱必信网站咨询 |