Ibrutinib-biotin,1599432-18-4

公告提醒：爱必信所有产品和服务仅用于科学研究，不用于临床应用及其他用途提供产品和服务（也不为任何个人提供产品和服务）!

YZ剂描述：

产品名称：Ibrutinib-biotin

产品别名：见爱必信官网

英文别名：Ibrutinib-biotin

靶点：Btk

CAS：1599432-18-4

纯度：98%

外观：见爱必信官网

保存方法：Store at -20°C

描述：

Ibrutinib-biotin is a probe that consists of Ibrutinib linked to biotin via a long chain linker, extracted from patent WO2014059368A1 Compound 1-5, has an IC50 of 0.755-1.02 nM for BTK. 

溶解性：DMSO : 50 mg/mL (45.56 mM; Need ultrasonic)

体外研究：

Ibrutinib-biotin (Compound 1-5) is a probe that consists of Ibrutinib linked to biotin via a long chain linker. Ibrutinib is a TEC family kinase inhibitor. The TEC kinase family is composed of five members, TEC, BTK (Bruton's Tyrosine Kinase), ITK (interleukin-2-inducible T-cell kinase)/EMT/TSK, BMX and TXK/RLK. The TEC family kinases participate in phosphotyrosine- mediated and phospholipid-mediated signaling systems. Many TEC family proteins are abundantly expressed in hematopoietic tissues, and play important roles in the growth and differentiation processes of blood cells.

体内研究：

产品信息订购：

产品更多信息请进入爱必信网站咨询