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YZ剂描述： 产品名称：Geneticin (G418 Sulfate) 产品别名：G-418 硫酸盐 英文别名：Geneticin sulfate;Antibiotic G-418 sulfate 靶点：Bacterial CAS：108321-42-2 纯度：98% 外观：白色粉末 保存方法： store at -20℃ for one year（Powder）； in DMSO or others solvent store at 2-4℃ for two weeks, at -80℃ for six months. 描述： G418 (Geneticin) is an aminoglycoside antibiotic similar in structure to gentamicin B1; blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells. 溶解性：Water：100mg/ml(144.36 mM) 体外研究： G418 is an inhibitor of many pro- and eukaryotes at concentrations from 1-300 microgram/ml. Resistance to G418 conferring by the neo gene from Tn5 encoding an aminoglycoside 3'-phosphotransferase, APT 3' II is commonly used in laboratory research to select genetically engineered cells. In general for bacteria and algae concentrations of 5 mg/L or less are used, for mammalian cells concentrations of approximately 400 mg/L are used for selection and 200 mg/L for maintenance. Resistant clones selection could require from 1 to up to 3 weeks. 体内研究：Doses of G418 of between 40 and 80 mg/kg for three consecutive days are sufficient to eliminate all nontransfected T. brucei brucei parasites from infected mice. 产品信息订购：
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