白细胞共同抗原抗体,Anti-CD45抗体

产品名称：白细胞共同抗原抗体,Anti-CD45抗体满意而归 
中文名称：白细胞共同抗原抗体  
英文名称：Anti-CD45
产品编号：byk-0522R 
产品规格：0.1ml/0.2ml
产品用途：科研实验
亚 型： IgG
贮 存： 贮存于-20℃
抗体的异质性。抗体的组成极为复杂，是由成千上万、多种多样的免疫球蛋白（Ig）分子所组成。这些Ig分子在形状、大小、结构以及氨基酸的组成和排列上，既相似，又有差别。由于有差别，它们的电泳活性就有很大的变化。
白细胞共同抗原抗体,Anti-CD45抗体满意而归  品说明：
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus belongs to receptor type PTP. This gene is specifically expressed in hematopoietic cells. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Four alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported.
保存条件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 
白细胞共同抗原抗体,Anti-CD45抗体满意而归 关产品：
Anti-MMP-26(Matrix metalloproteinase-26)  基质金属蛋白酶-26抗体
Anti-MMP-2(Collagenase IV /Gelatinase A/Metallo proteinase-2)  基质金属蛋白酶-2抗体
Anti-MMP-3(matrix metalloproteinase-3/Transin-1/SL-1/Stromelysin-1 precursor)  基质金属蛋白酶-3抗体
Anti-MMP-7(Matrilysin/matrix metalloproteinases-7)  基质金属蛋白酶-7抗体
Anti-MMP-8(Matrilysin/matrix metalloproteinases-8)  基质金属蛋白酶-8抗体
Anti-MMP-9(matrix metalloproteinase 9)  基质金属蛋白酶-9抗体
Anti-MMP-9(matrix metalloproteinase 9)  基质金属蛋白酶-9抗体
Anti-MMP-10(matrix metalloproteinase 10)  基质金属蛋白酶-10抗体
Anti-MMP-11(matrix metalloproteinase 11)  基质金属蛋白酶-11抗体
Anti-MMP-12(matrix metalloproteinase 12)  基质金属蛋白酶-12/巨噬细胞金属弹力蛋白酶抗体
抗体结构:
抗体是具有4条多肽链的对称结构，其中2条较长、相对分子量较大的相同的重链(H链)；2条较短、相对分子量较小的相同的轻链(L链)。链间由二硫键和非共价键联结形成一个由4条多肽链构成的单体分子。轻链有κ和λ两种，重链有μ、δ、γ、ε和α五种。 整个抗体分子可分为恒定区和可变区两部分。在给定的物种中，不同抗体分子的恒定区都具有相同的或几乎相同的氨基酸序列。可变区位于"Y"的两臂末端。在可变区内有一小部分氨基酸残基变化特别强烈，这些氨基酸的残基组成和排列顺序更易发生变异区域称高变区。高变区位于分子表面，多由17个氨基酸残基构成，少则只有2 ～ 3个。高变区氨基酸序列决定了该抗体结合抗原抗原的特异性。一个抗体分子上的两个抗原结合部位是相同的，位于两臂末端称抗原结合片段(antigen-binding fragment, Fab)。"Y"的柄部称结晶片段(crystalline fragment,FC)，糖结合在FC 上。