Mouse Cd14/Monocyte differentiation antigen CD14 ELISA Kit

产品类型：
ELISA kit
研究领域：

产品概述：
EK00333E is a ready-to-use microwell,strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the A Disintegrin and Metalloprotease 30 (Monocyte differentiation antigen CD14) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing Monocyte differentiation antigen CD14 The ELISA analytical biochemical technique of the EK00333E kit is based on Monocyte differentiation antigen CD14 antibody-Monocyte differentiation antigen CD14 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Monocyte differentiation antigen CD14 antigen targets in samples. The ELISA Kit is designed to detect native, recombinant, Monocyte differentiation antigen CD14 Appropriate sample types may include
细胞定位：
Cell membrane Lipid-anchor GPI-anchor Secreted Membrane raft Golgi apparatus Soluble, secreted forms seem to exist. They may arise by cleavage of the GPI anchor.
分析类型：
Sandwich
检测方法：
spectrophotometrical
反应性：
Mouse
检测范围："

0.625-40ng/ml
试剂盒组分：
Assay Plate, Standard, Sample Diluent, Assay Diluent A&B, Detection Reagent A&B, Wash Buffer, Substrate, Stop Solution.
基因名称：
Cd14
功能：
Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS) (PubMed:16148141). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (PubMed:8612135, PubMed:15895089). Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway (By similarity). Acts as an accessory receptor for M.tuberculosis lipoproteins LprA, LprG and LpqH, in conjunction with coreceptors TLR2 and TLR1. The lipoproteins act as agonists to modulate antigen presenting cell functions in response to the pathogen (PubMed:19362712). Binds electronegative LDL (LDL(-)) and mediates the cytokine release induced by LDL(-).
应用：
For research use only
联系方式：

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