Afatinib(439081-18-2)(≥99%)

特别提示：包括Afatinib在内，本公司的所有产品仅可用于科研实验，严禁用于临床YL及其他非科研用途！

产品名称：Afatinib
英文名称：Afatinib
产品货号：L10106
产品规格：5mg|10mg|50mg
 属性

CAS号	439081-18-2
分子式	C24H25ClFN5O3
分子量	485.94
溶解性	DMSO 97mg/mL Water<1 mg/mL Ethanol 15 mg/mL
存贮条件	储存温度-20℃

描述

应用	An irreversible and potent EGFR/Neu inhibitor,inhibits EGFR phosphorylation
产品介绍	Afatinib(BIBW2992) is an irreversible EGFR/Neu inhibitor with an IC50 of 14 nM.Afatinib is a potent inhibitor of EGFR phosphorylation.Afatinib showed positive results in assays against a variety of human cancer cell lines,including A431,murine NIH-3T3 cells,and breast cancer cell line BT-474.
备注	Afatinib(BIBW2992) irreversibly inhibits EGFR/HER2 includingEGFR(wt),EGFR(L858R),EGFR(L858R/T790M) and HER2 withIC50of 0.5 nM,0.4 nM,10 nM and 14 nM,respectively;100-fold more active against Gefitinib-resistant L858R-T790M E
别名	Tomtovok;阿法替尼;BIBW2992;N-[4-[(3-氯-4-fú苯基)氨基]-7-[[(3S)-四氢-3-呋nán基]氧基]-6-喹唑啉基]-4-(二甲基氨基)-2-丁xī酰胺;Tomtovok;(S,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide;BIBW2992

我公司销售的Afatinib(439081-18-2)(≥99%)，N-[4-[(3-氯-4-fú苯基)氨基]-7-[[(3S)-四氢-3-呋nán基]氧基]-6-喹唑啉基]-4-(二甲基氨基)-2-丁xī酰胺，Tomtovok，(S,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide，BIBW2992，阿法替尼质量上佳，价格普惠，欢迎广大新老客户踊跃订购。