Abiraterone Acetate(154229-18-2)(≥99%)

特别提示：包括Abiraterone Acetate在内，本公司的所有产品仅可用于科研实验，严禁用于临床YL及其他非科研用途！

产品名称：Abiraterone Acetate
英文名称：Abiraterone Acetate
产品货号：L10043
产品规格：100mg|5mg|25mg
 属性

CAS号	154229-18-2
分子式	C26H33NO2
分子量	391.55
溶解性	Soluble in methanol(sparingly),water(<1mg/ml at 25℃),DMF(~16 mg/ml),ethanol(28 mg/ml at 25℃),and DMSO(~2 mg/ml).
存贮条件	储存温度-20℃

描述

应用	A steroidal inhibitor of CYP17A1 in androgen biosynthesis
产品介绍	Abiraterone Acetate是Abiraterone的醋酸盐形式，是一种甾体类细胞色素CYP17YZ剂，IC50为72 nM。
备注	Abiraterone Acetate is an acetate salt form of Abiraterone which is a steroidal cytochromeCYP17inhibitor withIC50of 72 nM.
生化机理	Abiraterone acetate has been seen to be a novel steroidal inhibitor of CYP17A1(C17,20 lyase),a cytoochrome P450 complex,a rate-limiting enzyme in androgen biosynthesis resulting in inhibtion of testosterone production in both the adrenals and the testes.It has been observed to decrease the DHEA,androstenedione and testosterone.The compound has been shown to be approximately 21-24 times more potent than ketoconazole and liarozole in CYP17A1 lyase inhibition.In medicine,Abiraterone is used for treating prostate cancer.
别名	乙酸阿比特龙酯;CB 7630,CB-7630;(3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-(pyridin-3-yl)-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl acetate

我公司销售的Abiraterone Acetate(154229-18-2)(≥99%)，乙酸阿比特龙酯，CB 7630,CB-7630，(3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-(pyridin-3-yl)-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl acetate质量上佳，价格普惠，欢迎广大新老客户踊跃订购。